Delas Lab at University College London

Publications

You can find a selection and all our publications below. We are big fans of pre-prints, as they accelerate science and make it more accessible, and that is why you might find some of them twice.

Highlighted

The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
Isabel Zhang, Giulia LM Boezio, Jake Cornwall-Scoones, Thomas Frith, Ming Jiang, Michael Howell, Robin Lovell-Badge, Andreas Sagner, James Briscoe, M Joaquina Delas
Pre-print on biorxiv   ·   17 Apr 2024   ·   doi:10.1101/2024.04.17.589864
Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies
Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies
M. Joaquina Delás, Christos M. Kalaitzis, Tamara Fawzi, Madeleine Demuth, Isabel Zhang, Hannah T. Stuart, Elena Costantini, Kenzo Ivanovitch, Elly M. Tanaka, James Briscoe
Developmental Cell   ·   01 Jan 2023   ·   doi:10.1016/j.devcel.2022.11.016
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation
Robert Blassberg, Harshil Patel, Thomas Watson, Mina Gouti, Vicki Metzis, M. Joaquina Delás, James Briscoe
Nature Cell Biology   ·   01 May 2022   ·   doi:10.1038/s41556-022-00910-2
Repressive interactions in gene regulatory networks: When you have no other choice
Repressive interactions in gene regulatory networks: When you have no other choice
M. Joaquina Delás, James Briscoe
Current Topics in Developmental Biology   ·   01 Jan 2020   ·   doi:10.1016/bs.ctdb.2020.03.003

All

2024

The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
Isabel Zhang, Giulia LM Boezio, Jake Cornwall-Scoones, Thomas Frith, Ming Jiang, Michael Howell, Robin Lovell-Badge, Andreas Sagner, James Briscoe, M Joaquina Delas
Pre-print on biorxiv   ·   17 Apr 2024   ·   doi:10.1101/2024.04.17.589864

2023

Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies
Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies
M. Joaquina Delás, Christos M. Kalaitzis, Tamara Fawzi, Madeleine Demuth, Isabel Zhang, Hannah T. Stuart, Elena Costantini, Kenzo Ivanovitch, Elly M. Tanaka, James Briscoe
Developmental Cell   ·   01 Jan 2023   ·   doi:10.1016/j.devcel.2022.11.016

2022

Developmental cell fate choice employs two distinct cis regulatory strategies
Developmental cell fate choice employs two distinct cis regulatory strategies
M. Joaquina Delás, Christos M Kalaitzis, Tamara Fawzi, Madeleine Demuth, Isabel Zhang, Hannah T Stuart, Elena Costantini, Kenzo Ivanovitch, Elly M Tanaka, James Briscoe
Pre-print on biorxiv   ·   06 Jun 2022   ·   doi:10.1101/2022.06.06.494792
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation
Robert Blassberg, Harshil Patel, Thomas Watson, Mina Gouti, Vicki Metzis, M. Joaquina Delás, James Briscoe
Nature Cell Biology   ·   01 May 2022   ·   doi:10.1038/s41556-022-00910-2
Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells
Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells
Kathleen Shah, Muralidhara Rao Maradana, M. Joaquina Delàs, Amina Metidji, Frederike Graelmann, ..., Gavin Kelly, Chris Cheshire, Deendyal Bhurta, Sandip B. Bharate, Brigitta Stockinger
Nature Communications   ·   05 Apr 2022   ·   doi:10.1038/s41467-022-29098-7

2021

Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells
Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells
Kathleen Shah, Muralidhara Rao Maradana, M Joaquina Delas, Amina Metidji, Frederike Graelmann, ..., Ying Li, Mauro Tolaini, Michael Shapiro, Gavin Kelly, Brigitta Stockinger
Research Square Platform LLC   ·   02 Sep 2021   ·   doi:10.21203/rs.3.rs-827700/v1

2020

Sox2 levels configure the WNT response of epiblast progenitors responsible for vertebrate body formation
Sox2 levels configure the WNT response of epiblast progenitors responsible for vertebrate body formation
Robert Blassberg, Harshil Patel, Thomas Watson, Mina Gouti, Vicki Metzis, M Joaquina Delás, James Briscoe
Pre-print on biorxiv   ·   30 Dec 2020   ·   doi:10.1101/2020.12.29.424684
Repressive interactions in gene regulatory networks: When you have no other choice
Repressive interactions in gene regulatory networks: When you have no other choice
M. Joaquina Delás, James Briscoe
Current Topics in Developmental Biology   ·   01 Jan 2020   ·   doi:10.1016/bs.ctdb.2020.03.003

2019

lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation
lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation
M. Joaquina Delás, Benjamin T. Jackson, Tatjana Kovacevic, Silvia Vangelisti, Ester Munera Maravilla, Sophia A. Wild, Eva Maria Stork, Nicolas Erard, Simon R.V. Knott, Gregory J. Hannon
Cell Reports   ·   01 Apr 2019   ·   doi:10.1016/j.celrep.2019.03.080

2017

lncRNA requirements for mouse acute myeloid leukemia and normal differentiation
lncRNA requirements for mouse acute myeloid leukemia and normal differentiation
M Joaquina Delás, Leah R Sabin, Egor Dolzhenko, Simon RV Knott, Ester Munera Maravilla, ..., Inês AM Barbosa, Johannes Zuber, John L Rinn, Andrew D Smith, Gregory J Hannon
eLife   ·   06 Sep 2017   ·   doi:10.7554/eLife.25607
lncRNAs in development and disease: from functions to mechanisms
lncRNAs in development and disease: from functions to mechanisms
M. Joaquina Delás, Gregory J. Hannon
Open Biology   ·   01 Jul 2017   ·   doi:10.1098/rsob.170121

2015

Genome and transcriptome of the regeneration-competent flatworm,
            <i>Macrostomum lignano</i>
Genome and transcriptome of the regeneration-competent flatworm, Macrostomum lignano
Kaja Wasik, James Gurtowski, Xin Zhou, Olivia Mendivil Ramos, M. Joaquina Delás, ..., Peter Ladurner, Lukas Schärer, W. Richard McCombie, Gregory J. Hannon, Michael Schatz
Proceedings of the National Academy of Sciences   ·   21 Sep 2015   ·   doi:10.1073/pnas.1516718112

2013

Dogma Derailed: The Many Influences of RNA on the Genome
Dogma Derailed: The Many Influences of RNA on the Genome
Leah R. Sabin, M. Joaquina Delás, Gregory J. Hannon
Molecular Cell   ·   01 Mar 2013   ·   doi:10.1016/j.molcel.2013.02.010

2009

Yeast cultures with UCP1 uncoupling activity as a heating device
Yeast cultures with UCP1 uncoupling activity as a heating device
Joaquina Delás, Meritxell Notari, Jaume Forés, Joaquín Pechuan, Manuel Porcar, ..., Pedro Fernández de Córdoba, M. Mar González-Barroso, Eduardo Rial, Andrés Moya, Javier Urchueguía
New Biotechnology   ·   01 Dec 2009   ·   doi:10.1016/j.nbt.2009.09.005